Jananam is an exclusive and complete fertility centre off the East Coast Road in Neelangarai Chennai. Situated in Kazura garden first street, Jananam is in a peaceful neighbourhood, away from the buzz and pollution of the city.
Jananam Fertility Center, Chennai, Tamil Nadu - Service Provider of Andrology Medical Facilities, Tese Infertility Treatment, Freezing, Frozen Embryo Transfer and Medical Surgery & Treatment Centres
IUIINR0INR0What is Intrauterine Insemination (IUI)?
Intrauterine Insemination is often the initial approach to treating infertility. Although IUI has significantly lower success rates than IVF, many thousands of couples have conceived with this basic artificial insemination treatment. Success factors such as age, sperm quality and egg quality can influence the IUI pregnancy rates.
IUI is a procedure where sperm collected, prepared and inserted into the uterus of the female through a catheter. It is the closest fertility treatment to natural fertilization that would take place through intercourse as once inserted, the sperm must find its way, on its’ own, through the fallopian tubes to fertilize the egg. In some situations, IUI can include the use of fertility stimulation medications to increase the chances of pregnancy. IUI would not be recommended for women with damaged or blocked fallopian tubes.
When is IUI indicated?
A detailed fertility assessment will be done on both partners to determine the most appropriate treatment that is indicated based on results of the medical history and medical tests that are carried out. Our lead fertility specialist will discuss the options and advise a treatment procedure that is most likely to give you the best chance of conception.
IUI is indicated in the following candidates:
Couples with unexplained infertility who are unable to conceive for over a year.
Women with ovulation disorders, cervical abnormalities or mucus issues.
Male partner erectile dysfunction, premature ejaculation or inability to achieve orgasm during intercourse.
Male partner fertility issues such as low sperm count, low sperm motility, or abnormal sperm size and shape.
Couples with unspecified infertility who have been trying to have a baby for at least a year.True1519371555
IVFINR0INR0What is in vitro fertilization or IVF?
IVF is commonly known as ‘test tube baby’. It involves stimulating the ovaries to make multiple eggs grow and then taking the eggs out of the woman, fertilizing them in the laboratory with her partner’s sperm and transferring embryos back to her uterus. Egg + sperm form an embryo. The embryo implants in the uterus to grow into a baby.
The first IVF baby in the world (Louise Brown) was born in July of 1978 in England. Louise Brown was 28 when she delivered her own baby in 2006. Her baby was conceived by IVF. Hundreds of thousands of children are now born annually as a result of the IVF technique.
Who is treated with in vitro fertilization?
There are many reasons why IVF is advised. We have listed some of them below
ivf treatment Blocked fallopian tubes.
ivf-treatment Very low sperm counts – when the total motile sperm count is less than 1 million
ivf-treatment Failed intrauterine insemination (after 4-6 cycles)
ivf-treatment Advanced female age – over about 35 yrs of age with other reasons for infertility
ivf-treatment Reduced ovarian reserve – which means that there are reduced numbers of remaining eggs within the ovary
Chennai Best Test Tube Baby Centre Age > 35 years with other reasons for infertility
Chennai Best Test Tube Baby Centre Severe endometriosis
How does IVF improve your chances of getting pregnant?
In a woman who has regular periods a single egg is produced each month. This has to be transported through the tube. Sperms have to be present in adequate numbers and be able to swim through the uterus and reach the egg in the tube for union to occur. Once they unite to form an embryo, the embryo has to be transported to the lining of the uterus to implant and grow to form the baby.
In IVF we are compressing many months of ‘natural’ attempts into one cycle. In other words ivf-treatment We give hormone injections and stimulate the ovaries to produce many eggs – as opposed to a single egg forming in a natural cycle
IVF Clinic We take the eggs out when they are ready( bypassing the tubes )
IVF Clinic We facilitate fertilization by adding adequate sperms to each egg in a dish ( therefore the term test tube baby)
Chennai Best Test Tube Baby Centre We can check if the eggs are fertilized and select the best embryos to be replaced.
Chennai Best Test Tube Baby Centre We then transfer the best embryos into the cavity of the uterus
IVF Treatment Investigations
From the above it is clear that we need to check the following
Whether your ovary is producing eggs- by blood tests done on the second day and the 21st day of your period to measure your hormone levels and by doing a scan on day 2 to check the number of growing follicles
A seminal fluid analysis – This is done to assess the sperm count or numbers, sperm movement otherwise called motility and the morphology or appearance of sperms.
Tests to check whether the fallopian tubes are opened – called tubal patency tests. There are different types of tests which may be advised to check the tubes – a saline sonography, a hysterosalpingogram (HSG) or a laparoscopy.
Tests to check whether the uterus is normal – by doing a scan or a procedure called hysteroscopy
The choice of tests to be done will be discussed with you by your clinicianTrue1519371942
ICSIINR0INR0ICSI means injection of the sperm into the middle of the egg.
ICSI is an effective method to fertilize the egg.
How is ICSI done?
As with IVF, the ovaries are first stimulated by injections and eggs are retrieved.IVF with ICSI involves the use of specialized micromanipulator and an inverted microscope that enables embryologists to pick up individual sperms in a tiny specially designed hollow ICSI needle. The needle is then carefully advanced through the outer shell of the egg and egg membrane and the sperm is then injected into the inner part (cytoplasm) of the egg.
What percentage of eggs get fertilized after ICSI?
This usually results in normal fertilization in approximately 70-85% of eggs injected with viable sperm.
Who should be treated with ICSI?
Men with very low total motile sperm counts
IUI Treatment In couples who have had poor fertilization with IVF in a previous cycle
Emryo Transfer Men who have no sperms in their ejaculate but need removal from their testes (testicular sperms do not have the capacity to fertilize)
IVF Success Rate When fewer than 5 eggs have been retrieved – here ICSI is done to more eggs fertilized
IUI Success Rate When the number of eggs retrieved are less than 5. Here ICSI is used to get a higher percentage of eggs fertilized than with IVF (just mixing eggs and sperm together).
How is ICSI performed?
This is performed with a specialized ICSI microscope
Chennai Best Test Tube Baby Centre Under the microscope, the egg is held by a special holding pipette
Fertility Treatment Center A very fine needle is used to pick up the sperm and immobilize it
Fertility Clinic The needle with the sperm is introduced carefully through the outer layer of the egg(zonapellucida) and then into the cytoplasm of the egg
Fertility Centre in Chennai The sperm is then injected into the egg gently and the needle carefully removed
Fertility drugs for women The eggs are checked 18 – 20 hours later to see if they are fertilizedTrue1519372099
PICSIINR0INR0What is PICSI?
PICSI (Physiological ICSI) is a new micro-manipulative technique for identifying healthy, functional sperm for injection into mature egg, improving the chances of successful fertilization and also reduces the miscarriage risk.
How does PICSI influence IVF success rates?
PICSI increases the success rate by approximately 20% because it enables us to select and introduce a sperm to the oocyte based on its functional quality. This method works on the same principle by which sperms are selected in a woman’s body during the natural fertilization process.
When is PICSI Recommended?
This method is recommended in cases in which:
Sperm defect is suspected, for example sperm immaturity, chromosomal anomaly, a high degree of DNA fragmentation.
Low or poor fertilization with ICSI has occurred.
Poor embryo quality has been found.
Previous history of repeated implantation failure.
Repeated miscarriage has occurred.
PICSI is not feasible in patients for whom we aspirate sperms from the testis where most sperms are not motile and patients with ≤ 1million motile sperms in the final sample preparation.
What is difference between ICSI and PICSI?
During ICSI, motile sperms are selected for injection, based on their morphology and motility. This does not guarantee the introduction of a sperm with the optimum genetic package.
PICSI is a more refined procedure where we are able to determine sperm selection based on their function and it is similar to the process of sperm selection that happens during natural fertilisation. The selected sperm will have good DNA integrity and less incidence of DNA fragmentation.
What is PICSI procedure?
The PICSI procedure is the same as that of the ICSI, the only change being the method of selection of the male gamete.
The embryologist uses a PICSI dish, which is coated with drops of hyaluronan hydrogel. Hyaluronan is a naturally occurring bio polymer found in all human cells, including the gel layer surrounding the oocyte. The best – quality mature spermatozoa will get stuck to these hyaluronan and shows tails with hyper activation. Sperm showing this type of activation will be chosen for ICSI.
Once the spermatozoon has been selected, it is aspirated with the microinjection pipette and the regular ICSI is performed.True1519372532
FROZEN EMBRYO TRANSFERINR0INR0Frozen Embryo Transfer
Frozen Embryo Transfer (FET) is a process of thawing, culturing, and transferring embryos (Blastocysts) into the recipient’s uterus in a separate cycle from the IVF cycle.
In an FET cycle, the patient will not need to undergo ovulation induction or egg retrieval processes. The uterine receptivity will be examined and controlled by careful monitoring of the Fertility specialist to ensure readiness to receive the embryo. FET cycles usually involve fewer medication and costs are significantly lower as compared to a full IVF cycle.
Frozen embryo transfers also give couples the chance to have IVF cycles that are less costly than creating embryos through fresh new IVF cycles. This is because the thawing of embryos and the transfer process is more economical than a lengthy stimulation, egg retrieval and new IVF cycles.
The success of FET is on an average as good and sometimes better than fresh embryo transfers. The quality of the embryo plays a key role in the thawing process and good quality embryos have a high success rate of implantation.True1519372670
TESE & PESAINR0INR0TESE (Testicular sperm extraction) & PESA (Percutaneous epididymal sperm aspiration)
Among couples presenting for treatment at Jananam because of male infertility, some male partners have no sperms at all in their semen (a condition called azoospermia). This occurs in one in 100 men.
Fortunately, in most of these men sperm may be found in the epididymis (where sperms are stored) or the testicle (where sperms are produced). These sperms can fertilize an egg if directly injected into it using the ICSI technique.
Until this method was developed, such men were considered infertile and could not father children of their own. Today, many couples conceive with the assistance of TESE and ICSI at our medical center.
The extraction procedure is performed under local or general anesthesia. Testicular tissue is submitted to the IVF lab where it is scanned under a microscope and sperm is extracted. Usually, there is a small number of sperm in such a tissue sample, and some of them lack the capacity to move forward. Thanks to the ICSI technique, only one sperm is needed to fertilize each egg, and in most cases fertilization does occur with the development of an embryo. The unit is very experienced with this method, and the chances of conception are pretty good.True1519372902
DONORINR0INR0Some women need donated eggs or eggs from other women. We have listed a few reasons:
Women with premature ovarian failure – where eggs are absent in the ovaries before the age of 40 years.
Women who are above 40 years and do not have eggs.
Women with ovaries which have been removed for other reasons or destroyed by endometriosis.
Women who have some genetic diseases and are at risk of transmitting their problem to the offspring.
What is the success rate of egg donation?
Egg donation has a high success rate of about 55-60% and almost an 80 – 90% success rate after four repeated treatment cycles.
Can Jananam arrange egg donors?
Yes. We can egg donors for you. All our donors are less than thirty years old, and have one or two children. This ensures that they have eggs which are capable of being fertilized – a true test of their fertility
In couples who have had poor fertilization with IVF in a previous cycle
All our donors are screened extensively to rule out infections and hereditary diseases. We can match your blood group with the donor. We also try to match the recipient’s physical characteristics – height, complexion etc.
Will the donor remain anonymous?
Yes. The identity of egg donors will not be revealed. However we can disclose non identifying information about egg donors – namely their physical characteristics, education, hobbies etc.True1519373141
SurrogacyINR0INR0Can a surrogate mother be arranged by Jananam?
A surrogate mother is chosen after thorough screening for infectious diseases. In our centre, we have mothers who are usually less than 35 years old who have borne children (one or two). The surrogate mother is thoroughly counseled about the treatment and the consequences.
Consents are signed by all parties. This is a most important step in surrogacy cases. All potential issues need to be carefully clarified, put in writing, signed, and understood by all parties prior to initiation of the treatment.
The patient is stimulated with medications to develop multiple egg development.
The surrogate is placed on medications that thicken the uterine lining and also suppress her menses.
When the patient’s follicles are mature, egg pick up is performed to remove the eggs from her ovaries. The eggs are then fertilized in the laboratory with her partner’s sperm.
The embryos develop in the laboratory for 2- 3 days. Then, an embryo transfer procedure is done which places the embryos in the surrogate’s uterus where they will hopefully implant and develop to result in a live birth.True1519373389